Obesity and chronic disease in younger people: an unfolding crisis

Obesity and chronic disease in younger people: an unfolding crisis.

radical alterations in the factors determining energy intake and expenditure that we have witnessed over recent times have fundamentally changed the way we view the interplay between the environment and our physical selves. It was only at the advent of the 20th century that technological advancement finally began to squeeze out the manual labour associated with the production and transport of g...

Obesity and chronic disease in younger people.

Obesity and Kidney Disease

The rise in the prevalence of chronic kidney disease (CKD) and an increase in the prevalence of obesity in parallel in the recent years is a great concern. CKD increases the rate of cardiovascular disease (CVD) and development of end-stage renal disease, and leads to premature death. Although no direct causality link between obesity and CKD can yet be established, this appears highly probable. ...

Obesity and chronic kidney disease.

BACKGROUND/AIMS The prevalence of obesity among U.S. adults has doubled within the past two decades, and if trends continue, over one-third of U.S. adults may be obese by the year 2008. Concurrent with the rising prevalence of obesity is an epidemic of chronic kidney disease (CKD) with an estimated 18 million U.S. adults currently affected. This review discusses the strong and consistent associ...

Obesity and chronic kidney disease.

Obesity is associated with the early onset of glomerulomegaly, hemodynamic changes of a hyperfiltering kidney, and increased albuminuria, which are potentially reversible with weight loss. However, pathologic lesions of focal segmental glomerulosclerosis develop in experimental models of sustained obesity, and are observed in morbidly obese humans presenting with massive proteinuria. In additio...